So, I've killed Dredmor 3 times before, but that was on lower difficulties. Never fought him on Hard before, and never in a straight up fight.
This time he eats 3 Bolts of Mass Destruction, and about a half-a-dozen Bolts of Squid. They hardly affect him. Holy Hand Grenades make a bigger dent in his HPs, which is a bit surprising, given how crap they are against most else.
I swap out my Filigreed Silver Shield for A Mirror Darkly Shield. Magic Reflect tech against Dredmor. Then proceed to toss mechanical sawblades at him. Unlike the bolts, these make use of my tremendous Melee Power.
Still, Dredmor does more damage. His lightning bolt takes off about half my HPs? That Hallowed Circle buff from the Demonology tree is REALLY helpful here.
The result?
Spoiler
Show
http://i.imgur.com/V24hu.png
Full moon's light is calling me
My kingdom lies within
The mystic soul and lion's heart
Brought by the talisman
The ecstasy of battle takes me
Where the falcons fly
Immortal youth was granted me
I will never die
So anyways, I'm pretty proud of myself. But yeah, those sawblades finished him off. Still have never (successfully, you may note Vlad on that high score chart) engaged Dredmor in melee. Though I think I might have stood a chance with the protective circle. I kind of wanted to try Diggle Hell, but some of those caster Diggles actually hurt.
Finished with all my skills maxed, except the last in Viking Wizardry, the last two in Necronomiconomics, and the Demonic half off Demonology.
So ends the story of Immortal, the truest of the true, the most metal character I have ever played in Dungeons of Dredmor.