The only problem with that is, while yes, I absolutely agree. In practice, it doesn't quite work. Everytime someone has gone against the Imperium, they always end up turning to Chaos anyway (i.e; Alpharius, Curze, Huron, Sarpedon, etc.) even though that's probably not how they start, it's how they end.
So far, the only canon examples for turning against the Imperium, is turning to Chaos. Even the Relictors did it. Although there is that one time where the planet turns to the Tau...But that turns out to be a Genestealer Cult, so it's hard to know what the 'choice' was.