Unfortunately, the Word of God has explicitly stated that this is not the case and that meat-space humans are the majority of the 1:1 intelligences
I bet most transcendiis are hanging around in the virtualverse rather than meatspace. If you're interested in radically redefining your perceptions, intelligence and experiences, doing it in the real world doesn't sound like it would help that much.

Quote Originally Posted by Fan
That sounds like a critical flaw in the Culture's understanding of the spiritual side of the universe though, not a problem on the 40k side. The 40k side is the one with all of the metaphysical knowledge, and I don't see a reason for the metaphysical side that has stated things to be ousted in favor of the other side with no stated, or existing, metaphysical concepts.
The Sublime is all metaphysical concepts, and AI explicitly can exist in the sublime, and each individual copy of a personality will be combined into one so it doesn't matter how many you make. But we've basically excised the Sublime from this fic. Or alternatively, we're basically asking a hypothetical question about how people would react if the Sublime was evil.