Results 1 to 5 of 5
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2018-12-09, 01:15 PM (ISO 8601)Bugbear in the Playground
- Join Date
- Jan 2013
- Location
- Arkansas, U.S.
- Gender
Would an Sn2 reaction work with H2NROR and MeI?
I was thinking.... H2MeN+ROR and I- as a result of such a reaction?
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2018-12-09, 05:01 PM (ISO 8601)Troll in the Playground
- Join Date
- Oct 2014
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- Tulips Cheese & Rock&Roll
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Re: Would an Sn2 reaction work with H2NROR and MeI?
Is this a serious chemistry question, or some sort of He-Man joke?
The Hindsight Awards, results: See the best movies of 1999!
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2018-12-09, 10:03 PM (ISO 8601)Bugbear in the Playground
- Join Date
- Jan 2013
- Location
- Arkansas, U.S.
- Gender
Re: Would an Sn2 reaction work with H2NROR and MeI?
Serious question. :P
I never watched He Man, so I wouldn't know the references.
H2N bonded to Any Ether
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2018-12-10, 10:02 AM (ISO 8601)Pixie in the Playground
- Join Date
- Feb 2015
Re: Would an Sn2 reaction work with H2NROR and MeI?
Yes that is correct It would go with SN2 mechanism
Going more in deep, a reaction like
CH3O(CH2)nNH2 + MeI
Would work better with big n, so there is more distance between the nitrogen and the oxygen and the ammine is a better nucleophile. Also a polar solvent would help the reaction.Last edited by Ciffo; 2018-12-10 at 10:10 AM.
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2019-01-22, 10:25 AM (ISO 8601)Dwarf in the Playground
- Join Date
- Mar 2011
- Gender
Re: Would an Sn2 reaction work with H2NROR and MeI?
Yes, but you should note that it would occur up three times.
First one would: Me-HNROR + HI
second one: Me2-NROR + HI
third one: Me3-N+ROR I- (Quaternary salt)
reaction conditions (time and solvent) could select one.
need a basic medium, or else you do a Ether Cleavage in parallel
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