I *think* that Brun's dialogue in the last panel is a quote from a movie or book. I feel that I recognise it, but I can't place the reference.

Don't know about the glowing 'anime'-style eyes though, I thin that's just a meme. Either that or Jeph "I have an addictive personality" Jacques went through some really weird times before he moved onto, and then eventually away from, alcohol.