Quote Originally Posted by Pie Guy View Post
As a Massachusetts resident, I don't think that would be a good idea. The city of Boston itself is pretty small, and the metro area is extremely urban. It would pretty much be like if the entire game was set in Freeside.

Edit: As evidence, just look at Google Earth over Boston. Even the sections that look like trees have houses and churches in them.
DC and New Vegas weren't the whole of their games, either. Frankly, a small, densely packed major city would suit them better than a large one, as they'd have to condense it less to make it usable.