R'yleh
Dave attempts to stop her! Mostly by trying to gently grab her.
"Woah now. Clarissa, we can't bail out of this appointment. I may not want to be in this crazy place that much, but you do need a check-up. Can we please just get through it? I promise I'll do whatever you want afterwards."
Good job, Dave! You save the Nexus!
Though by being married to Clarissa in the first place, he's probably made her much more sane and has already saved the Nexus, numerous times