Originally Posted by
Anarion
I think it's misleading to say that the Fallout games don't take themselves seriously. They do parody several things, such as using a proxy for Coca-Cola bottlecaps as their currency, referencing all the old Cold War black and white films, using old green-text computes, and having several horribly disfigured people do their comic relief. But the world of Fallout is a world where people laugh, so that they don't cry. Because if you actually take the time to look at what is, and compare it to what was, the loss is staggering. If you have a chance, go pick up Fallout 3. Turn off the radio so there's no jaunty music. Put away all the happy vault-tec figures and 1950s clothing and naming. Then, walk around, look at the towns, at the vaults, at the world. It's not pretty.
I haven't read Fallout: Equestria. But, if as Thanqol says, it managed to capture that feeling of Fallout and somehow make it work with ponies, of all things, that is really impressive.