Given it's DOE funded, I'm guessing a big focus will be on energy storage and generation materials, possibly some climate work, radiation modelling, and/or particle physics simulations or data collation is also a possibility. In short, it'll be for whatever gets the computing time grants funded.
I also read recently that there's a new supercomputer online at the University of Wyoming, called Yellowstone, that will be the first of its kind to be solely dedicated to geoscience research.
EDIT: Oh, it's specifically ORNL, which means it will almost certainly see a lot of work in the nuclear sciences.