We do not really know, but it is highly likely that the IFCC set V up specifically so that Familicide would annihilate Clan Draketooth. All they had to do was help a few of the right scrolls fall into the hands of that Black Dragon, help her find the target for her revenge, and include the right epic soul within the splice deal.
No, they said specifically that they didn't actually expect V's alignment to change, they were very much NOT planning for Familicide.
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English isn't my primary language, so please let me know if something I'm saying doesn't make sense!