You are looking for something rules light, since an increase in the number of rules in use will increase the number of artifacts encountered. The only other option is to use a setting that encourages a physicalist interpretation of the rules wherein the results generated by the rules are explicitly favored over "realism", because the setting possesses inherent unrealism in ways which favor reliance on the rules to determine results.
Your players lists are generally supporting a desire to play a science-fantasy setting; this is an area that I don't normally track because of the preferences of the people i've gamed with.