Here are some ideas I have;

The four players awake on an alien ship with semi-amnesia. They have no clue what race/faction this ship belongs to. An unknown alien being walks in who speaks a strange language they have Never before heard. He reaches down to his side and pulls out a laser scalpel. Combat begins. After killing/subduing this opponent they must find a way off the ship.

The players have been sent on a mission to smuggle a large and strange looking container to a group of drug dealers. On this mission they must fight off dire corby pirates, a small pack of void-barracudas, and finally a party of bounty hunters who claim that they are charged with multiple counts of smuggling and illegal void-hunting. If at any point they check what is in their package they will find a small puddle of ooze, any attempts to communicate with it will cause the ooze to take the form of a small child who speaks telepathically. It tells them that it is a powerful psychic that is being sold to a cartel to catalog possible police incursions. If they do nt open the ooze will either escape and turn on them, or it will be sold to the cartel and they will receive a hefty payment.