Also I wonder how cross-blood bloodlines work with Spheres of power.

Starting with the main version by looking at the Sorcerer

A crossblooded sorcerer has one fewer spell known at each level (including cantrips) than is presented on Table: Sorcerer Spells Known.

Furthermore, the conflicting urges created by the divergent nature of the crossblooded sorcerer’s dual heritage forces her to constantly take some mental effort just to remain focused on her current situation and needs. This leaves her with less mental resolve to deal with external threats. A crossblooded sorcerer always takes a –2 penalty on Will saves.
How does this work with Spheres? do they lose like half their talents to crossblood?

This question seems even stranger for Incanter Specializations. What losses do they have for grabbing powers from 2 bloodlines but taking them mutually exclusively (Like taking the Orc and Draconic bloodlines so they could replace the breath weapon with Strength bonuses and replace size change with wings)