Just caught this today.
Spoiler: The Issue of Inconsistency.
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I have to admit I didn't see it when I watched the episode, but it's really glaring now. I mean wow.
At the moment the best excuse I can come up with (and it's a weak one) is that locking Mack up was a simple, quick action. One push, jump back, close door in real time. No effort to make any complicated actions in hyperspeed, nothing requiring complex coordination anyway. And it still apparently created neural anomaly, as Androgeus points out, just a subtle one that was misconstrued. Remember that Fitz-Simmons wasn't saying that her powers where now unusable, just that [Garrus]calibrations[/Garrus] would be required to fix the problem. So... it could work if you're willing to make enough assumptions for it.