This is larger scale than most, but small scale in the context of the campaign.

I'm running a Prime Directive game (set fairly early, around the time Pike has the Enterprise) at the moment, and I've decided to delete some of the nations (Right now, only the Klingons, Romulans, Kzinti, and Federation are confirmed to exist) and add others to keep an air of mystery.

One of the new nations is a time-displaced accidental Vulcan-Human-Klingon colony that is essentially a typical D&D setting with Star Trek technology - the Vulcans and Klingons are even called Elves and Orcs. Not the nost original of ideas, but I'm pretty pelased.that I made it work.