Alright then. Find me a panel in which A requests that B do something, and B does something in the next panel that complies with what A asked as though one word was replaced with an anagram of itself.
Example
A: I don't know how to do this, can you give me some tips?
B: Hands over a glass of saliva, or, some spit.
The anagram-reaction doesn't have to be instead of what B requested; it can also be as well as. In the example, B could have given some tips along with the glass of saliva.
The word that is subjected to the anagram must be at least three letters long.
Spoiler: First hint
Show
A has been alive for the full duration of the comic, in part thanks to an insubordinate underling or two.
B was alive when the comic started, but is dead now.
Spoiler: Second hint
Show
A wants B to stop behaving in a certain way. B stops carrying something. This something would eventually become very treasured by an OotS member.