At the end of the day, I think that preserving anything about the universe has to be compared to the alternatives in order to reach a sensible judgment. Hopefully we can all agree on that.
aje8 makes a valid point. Often, moral dilemmas will be given with the stipulation, either explicit or implied, "Assume that you are acting with perfect knowledge of the situation and are justifiably certain of everything that I'm about to say. Even though there's no conceivable way that that could be true". Maybe, just for fun, we should try not doing that this time.
OK, the Auditors and the Doomguard I know, but where are Proteans from?
Contraception isn't murder. There are important similarities; for example, in each case someone would have been alive but instead isn't. But there are also important differences; for example, killing someone without his permission is coercive, but bringing a new mind into existence is also coercive, as consciousness is forced onto the created individual without its consent. (One could perhaps get around this by designing a mind to be consenting to its existence at the moment that it began operation.) Both the similarities and the differences should be given proper ethical consideration.
I like the way you think, my good sir.
If there's a Creator, It has a heck of a lot to answer for.
Selfishness is not caring about anyone else. And it's Neutral, not Evil. (Evil means trying or at least wanting to harm others.)
"If God had not meant for there to be a smallpox, Dr. Jenner, he would not have placed it upon the Earth."
Natural laws do not need to be enforced. They are not the sort of rules that can be violated. They describe how things do happen. Were a violation of the conservation of momentum to be discovered, that would simply demonstrate that conservation of momentum is not an absolute, universal law. By definition. A working perpetual motion machine would not be immoral simply because it would violate well-established scientific consensus. The notion is absurd.
So I think that the proper response to that criticism -- one that E.J. actually faced, if I'm recalling a biography of him correctly -- is that if God doesn't want smallpox to be eliminated, then it won't be. And that if God didn't want anyone to try to get rid of it, then he wouldn't be doing that. Indeed, there rather seems to be an inherent problem with the notion of defying the will of an omnipotent being. Or a fundamental law of the cosmos, if you prefer. We are part of the universe; we do not interfere in it from outside of it.
Human beings are sort of distinguished by a tendency to not idly allow things to take their course. We build, we rule, we control, we alter. We attempt to reshape the world according to our will. Sometimes these efforts are misguided. But not to the extent that civilization is inherently bad.
"If you take common sense and rigorously apply it, through multiple inferential steps, to areas outside everyday experience, successfully avoiding many possible distractions and tempting mistakes along the way, then it often ends up as a minority position and people give it a special name."
– Eliezer Yudkowsky